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  4. Cetin Lab. on Nanophotonics and Biodetection Systems


TECHNOLOGICAL RESEARCH PROGRAM
Erdal Lab. Guven Lab. Kocer Lab. Tozburun Lab. IBG-BIP Ayar-Kayali Lab. Cetin Lab. Karakülah Lab.

Cetin Lab. on Nanophotonics and Biodetection Systems

OVERVIEW

The process of developing biosensors requires fundamental research on plasmonics so that new functionalities can be achieved that are not available with the conventional approaches. In Nanophotonics and Biodetection Systems Laboratory, we utilize nano-plasmonics to develop ultra-sensitive spectroscopy and sensing technologies for real-time, label-free and high-throughput detection and analysis of very low quantities of biomolecules. In order to achieve large sensitivities, high-quality factor plasmonic structures supporting extremely sharp spectral features with strong nearfield responses are explored. The sensing platforms utilizing these plasmonic structures allows stronger analyte-field overlap, which leads strong spectroscopy and sensing signals, easily distinguishable by detectors.

RESEARCH HIGHLIGHTS

PLASMONIC HAND-HELD BIOSENSORS FOR FIELD SETTINGS
In the conventional spectrometer-based read-out schemes that utilize refractive index sensing, the presence of biomolecules is measured by monitoring spectral shifts within the optical response of the plasmonic structures. These platforms can enable analyte sensing, i.e., viruses or bacteria, from biological media at clinically relevant concentrations with little to no sample preparation. Multiplexing and high-throughput capability of these biosensors can be improved via integrating large scale and highly dense plasmonic chips to imaging based platforms, i.e., CCD or CMOS cameras. These biosensors can be also portable to be employed in the resource-poor settings by integrating plasmonic chip technology with lensfree telemedicine technology. This handheld design can be integrated with portable read-out-devices, e.g., a laptop or a cell-phone, that enables detection of biomolecules with a multiplexed manner in any environment, lack of medical infrastructure. This system can also enable parallel detection of different biomolecules with ultra-thin layers as well as quantitative analyses of single-type biomolecules with large variety of concentrations. We also investigate fluidic systems integrated with plasmonic chip technology for efficient analyte-delivery, yielding ultra-fast sensor response. Integrating microfluidics with plasmonic handheld technology, we also demonstrate real-time analyses of protein-protein interaction kinetics in a cost-effective and high-throughput manner. Utilizing robust and smart algorithms, this microfluidic technology allows to monitor biomolecular binding interactions at pMolar levels.

Group Members

Cetin Lab. on Nanophotonics and Biodetection Systems

Research Group Leader

Arif Engin ÇETİN
arifengin.cetin@ibg.edu.tr
+90 232 299 41 00 (5161)
 +9 0 (232) 299 41 66

  1. Cetin Lab. on Nanophotonics and Biodetection Systems

MERYEM BEYZA AVCI Researcher  beyza.avci@ibg.edu.tr


BİLGE CAN Researcher  bilge.can@ibg.edu.tr


Damla AYDOĞAN ÇAM Visiting Researcher  damla.aydogan@ibg.edu.tr


Furkan KOÇER MSc Student  furkan.kocer@ibg.edu.tr


Fatma KURUL Researcher  fatma.kurul@ibg.edu.tr

0 (232) 299 _ _

Aslı BARDAK Undergraduate Student  None


Seda DAYAL Visiting Researcher  None


Former Members

BİLGE CAN Research Technician  bilge.can@ibg.edu.tr


BİLGE CAN Research Technician  bilge.can@ibg.edu.tr


Şevin AY MSc Student  sevin.ay@msfr.ibg.edu.tr


Sedanur TOPKAYA ÇETİN Researcher  sedanur.cetin@msfr.ibg.edu.tr


Ece CESUR Researcher  ece.cesur@ibg.edu.tr


BİLGE CAN Visiting Researcher  bilge.can@ibg.edu.tr


ONUR AKDEMİR Undergraduate Student  onur.akdemir@ibg.edu.tr


Dilan DOĞRU Undergraduate Student  dilan.dogru@msfr.ibg.edu.tr


MERYEM BEYZA AVCI Undergraduate Student  beyza.avci@ibg.edu.tr


Mehmet Furkan ÇOLAK Undergraduate Student  furkan.colak@ibg.edu.tr


Ayça Kulpedin Undergraduate Student  ayca.kulpedin@ibg.edu.tr


Fatma KURUL MSc Student  fatma.kurul@ibg.edu.tr

0 (232) 299 _ _

Rabia HAMURCU Undergraduate Student  rabia.hamurcu@ibg.edu.tr


Sena YAMAN Post-Doc Researcher  sena.yaman@msfr.ibg.edu.tr


Özge Ada BOZBAŞ Undergraduate Student  ozge.bozbas@ibg.edu.tr


MERYEM BEYZA AVCI MSc Student  beyza.avci@ibg.edu.tr


Hezzal KÜÇÜKSELBES Undergraduate Student  hezzal.kucukselbes@ibg.edu.tr


Emine KARAARSLAN Undergraduate Student  emine.karaarslan@ibg.edu.tr


Emine KARAARSLAN Undergraduate Student  emine.karaarslan@ibg.edu.tr


Rabia HAMURCU Undergraduate Student  rabia.hamurcu@ibg.edu.tr


Hezzal KÜÇÜKSELBES Undergraduate Student  hezzal.kucukselbes@ibg.edu.tr


ONUR AKDEMİR Visiting Researcher  onur.akdemir@ibg.edu.tr


Ayça Kulpedin Visiting Researcher  ayca.kulpedin@ibg.edu.tr


Miraç KILIÇ Undergraduate Student  None


Miraç KILIÇ Undergraduate Student  None


Uğur DURA Visiting Researcher  ugur.dura@ibg.edu.tr


Emre GÜRALP Undergraduate Student  emre.guralp@ibg.edu.tr


Sinem ÖZEN Undergraduate Student  sinem.ozen@ibg.edu.tr


Sevim Deniz YAŞAR Undergraduate Student  sevimdeniz.yasar@ibg.edu.tr


Ali Ahmet ERDOĞDU Undergraduate Student  ali.erdogdu@ibg.edu.tr


Cansu ÇELEBİOĞLU Undergraduate Student  cansu.celebioglu@ibg.edu.tr


Hezzal KÜÇÜKSELBES Visiting Researcher  hezzal.kucukselbes@ibg.edu.tr


Özge Ada BOZBAŞ Visiting Researcher  ozge.bozbas@ibg.edu.tr


Ali Ahmet ERDOĞDU Undergraduate Student  ali.erdogdu@ibg.edu.tr


Özge Ada BOZBAŞ MSc Student  ozge.bozbas@ibg.edu.tr


Duygu GENÇER Undergraduate Student  duygu.gencer@ibg.edu.tr


Canberk SAYAR Visiting Researcher  canberk.sayar@ibg.edu.tr


Alperen GÖCEN Visiting Researcher  alperen.gocen@ibg.edu.tr


Sevim Deniz YAŞAR Visiting Researcher  sevimdeniz.yasar@ibg.edu.tr


Ece Minel BURSALI Undergraduate Student  eceminel.bursali@ibg.edu.tr


Duygu ÇATKIN Undergraduate Student  duygu.catkin@ibg.edu.tr


İbrahim KABA Undergraduate Student  ibrahim.kaba@ibg.edu.tr


Bedia Nur ELMAS Undergraduate Student  nur.elmas@ibg.edu.tr


Duygu ÇATKIN Visiting Researcher  duygu.catkin@ibg.edu.tr


Alperen GÖCEN Undergraduate Student  alperen.gocen@ibg.edu.tr


Ece Minel BURSALI Undergraduate Student  eceminel.bursali@ibg.edu.tr


Mehmet KOCAGÖZ MSc Student  mehmet.kocagoz@std.ibg.edu.tr


Sude KURT Undergraduate Student  None


Zeynepsu OLUK Undergraduate Student  zeynepsu.oluk@std.ibg.edu.tr


Selected Publications

Huseyin Oguzhan Kaya, Yamac Tekintas, Fatma Kurul, Arif E. Cetin, and Seda Nur Topkaya. Targeted microorganism detection with molecularly imprinted polymer biosensors. Journal of Electroanalytical Chemistry. 2030 January . Download

Melih Manir, Gamze Genç, Vagif Nevruzoglu, Murat Tomakin, Arif E. Cetin. Fabrication of gold thin films on cooled glass substrates. Plasmonics. 2024 January . doi:10.1007/s11468-024-02302-8. Download

Idil Karaca Acari, Fatma Kurul, Meryem Beyza Avci, S. Deniz Yasar, Seda Nur Topkaya, Ceyhun Acari, Erbil Unsal, Balahan Makay, Suleyman Koytepe, Burhan Ates, Ismet Yılmaz, Turgay Seckin, Arif E. Cetin. A plasmonic biosensor pre-diagnostic tool for Familial Mediterranean Fever. Nature Communications. 2024 October . Download

Elif Lulek, Arif E. Cetin and Yavuz Nuri Ertas. Label-free Biosensing Using Hybrid Plasmonic Substrates Generated via Nanosphere Lithography. ACS Applied Nano Materials. 2024 October . Download

Gorkem Liman, Emre Ergene, Emrecan Yildiz, Kubra Ozkan Hukum, Pinar Yilgor Huri, Arif E. Cetin, Hakan Usta, Gokhan Demirel. Dynamic Tuning of Plasmonic Hot-Spot Generation through Cilia-Inspired Magnetic Actuators. Advanced Intelligent Systems. 2023 March ; 5 (6) : 2200420. doi:10.1002/aisy.202200420. Download

Meryem Beyza Avci, S. Deniz Yasar, Arif E. Cetin. An Optofluidic Platform for Cell-Counting Applications”, , doi: 10.1039/D3AY00344B (2023).. Analytical Methods. 2023 April ; 15 (18) : 2244-2252 . doi:10.1039/D3AY00344B. Download

Fatma Kurul, Huseyin Istanbullu, Huseyin Oguzhan Kaya, Arif E. Cetin, Seda Nur Topkaya. Electrochemical Properties of Fused Pyrimidine-Triazole Heterocyclic Molecules as Novel Drug Candidates”, doi: (2023).. Turkish Journal of Pharmaceutical Sciences. 2023 May . doi:10.4274/tjps.galenos.2023.46095. Download

Arif E. Cetin, Seda Nur Topkaya, Ziya Ata Yazici, Ozden Yalcin-Ozuysal. Plasmonic Functional Assay Platform Determines the Therapeutic Profile of Cancer Cells. ACS Sensors. 2023 July ; 8 (7) : 2543-2555. doi:10.1021/acssensors.3c00208. Download

Vagif Nevruzoglu, Murat Tomakin, Melih Manir, Selcuk Demir, Fatih Saban Beris, Arif E. Cetin. Enhancing Label‑Free Biosensing With Cryogenic Temperature‑Induced Plasmonic Structures. Plasmonics. 2023 July . doi:10.1007/s11468-023-01963-1. Download

Arif E. Cetin. A Portable Plasmonic Biosensor Kit for Diagnostics of Sexually Transmitted Infection. Plasmonics. 2023 September . doi:10.1007/s11468-023-02035-0. Download

Sena Yaman, Meryem Beyza Avci, Fatma Kurul, Seda Nur Topkaya and Arif E. Cetin. Handheld Optofluidic Platform towards Binding Dynamics Applications in Field-Settings. Sensors and Actuators A: Physical. 2023 December ; 363 : 114685. doi:10.1016/j.sna.2023.114685. Download

Arif E. Cetin. A portable and low-cost incubator system enabling real-time cell imaging based on a smartphone. Turkish Journal of Physics. 2023 October ; 47 (5) : 279-296. doi:10.55730/1300-0101.2749. Download

Arif E. Cetin. A Novel Triazolopyrimidinone Derivative: A Portable Electrochemical Approach to Investigate DNA Interactions. Cumhuriyet Science Journal. 2023 December ; 44 (4) : 617-624. doi:10.17776/csj.1344756. Download

Seda Nur Topkaya, Idil Karaca Acari, Huseyin Oguzhan Kaya, Imren Ozcan, Suleyman Koytepe, and Arif E. Cetin. Interaction of Nickel Ferrite Nanoparticles with Nucleic Acids. Colloids and Surfaces B: Biointerfaces. 2022 March ; 211 : 112282. doi:10.1016/j.colsurfb.2021.112282. Download

Zhiliang Zhang, Feng Zhao1, Renxian Gao, Chih-Yu Jao, Churong Ma, Jie Li 1, Xiangping Li, Bai-Ou Guan, Arif E. Cetin, Kai Chen. Rayleigh Anomaly-Enabled Mode Hybridization in Gold Nanohole Arrays by Scalable Colloidal Lithography for Ultra-sensitive Biosensing. Nanophotonics. 2022 January . doi:10.1515/nanoph-2021-0563. Download

Meryem Beyza Avci, Rabia Hamurcu, Ozge Ada Bozbas, Ege Gurman, Arif E. Cetin, Ebru Sayilgan. Design of Steady-State Visually-Evoked Potential Based Brain-Computer Interface System. Journal of Intelligent Systems With Applications. 2022 January ; 5 (2) : 86-89. doi:10.54856/jiswa.202212214. Download

Huseyin Oguzhan Kaya, Arif E. Cetin, Mostafa Azimzadeh, and Seda Nur Topkaya. Pathogen Detection with Electrochemical Biosensors: Advantages, Challenges and Future Perspectives. Journal of Electroanalytical Chemistry. 2021 February ; 882 (1) : 114989. doi:10.1016/j.jelechem.2021.114989. Download

Huseyin Oguzhan Kaya, Arif E. Cetin, and Seda Nur Topkaya. Electrochemical Detection of Linagliptin and Its Interaction with DNA. Turkish Journal of Pharmaceutical Sciences. 2021 March . doi:10.4274/tjps.galenos.2021.71354. Download

Yeni Wahyuni Hartati, Seda Nur Topkaya, Shabarni Gaffar, Husein Hernandi Bahti, Arif E. Cetin. Synthesis and Characterization of Nanoceria for Electrochemical Sensing Applications. RSC Advances. 2021 April ; 11 (27) : 16216-16235. doi:10.1039/D1RA00637A. Download

Gorkem Liman, Emrecan Yildiz, Hasan Ilhan, Arif E. Cetin, Gokhan Demirel. Hot-Spot Engineering Through Soft Actuators for Surface-Enhanced Raman Spectroscopy (SERS) Applications. ADVANCED OPTICAL MATERIALS. 2021 May . doi:10.1002/adom.202100009. Download

Arif E. Cetin, Seda Nur Topkaya, Ozden Yalcin-Ozuysal, Ali Khademhosseini. Refractive Index Sensing For Measuring Single Cell Growth. ACS NANO. 2021 May . doi:10.1021/acsnano.1c04031. Download

Ayca Karasakal, Sulinay Parlar, Vildan Alptuzun, Arif E. Cetin, and Seda Nur Topkaya. A Novel Molecule: 1-(2,6 dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium chloride and its Interaction with DNAA Novel Molecule: 1-(2,6 dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium chloride and its Interaction with DNA. ELECTROANALYSIS. 2021 May . doi:10.1002/elan.202060597. Download

Maryam Daneshpour, Zhina Mazhari, Melika Haji Mohammadi, Arif E. Cetin, Maedeh Khodamoradi, Amir Reza Aref, Mostafa Azimzadeh, and Seda Nur Topkaya. Review of Current Diagnostics Developed for COVID-19. Analytical and Bioanalytical Chemistry Research. 2021 June ; 8 (4) : 417-444. doi:10.22036/ABCR.2021.271340.1593. Download

Arif E. Cetin, Zeynep A. Kocer, Seda Nur Topkaya, Ziya Ata Yazici. Handheld Plasmonic Biosensor for Virus Detection in Field-Settings. Sensors and Actuators B: Chemical. 2021 October ; 344 : 130301. doi:10.1016/j.snb.2021.130301. Download

Seda Nur Topkaya, Ezgi Turunc, Arif E. Cetin. Multi-Walled Carbon Nanotubes and Gold Nanorod Decorated Biosensor for Detection of microRNA-126. Electroanalysis. 2021 July . doi:10.1002/elan.202100198. Download

Arif E. Cetin, Cihan Yilmaz, Betty C. Galarreta, Gizem Yilmaz, Hatice Altug and Ahmed Busnaina. Fabrication of Sub-10 nm Plasmonic Gaps for Ultra-Sensitive Raman Spectroscopy. PLASMONICS. 2020 February . doi:10.1007/s11468-020-01137-3. Download

Seda Nur Topkaya, Ayca Karasakal, Arif E. Cetin, Sulunay Parlar, and Vildan Alptuzun. Electrochemical Characteristics of a Novel Pyridinium Salt as a Candidate Drug Molecule and Its Interaction with DNA. ELECTROANALYSIS. 2020 April ; 32 (8) : 1780-1787. doi:10.1002/elan.202000012. Download

Seda Nur Topkaya and Arif E. Cetin. Electrochemical Aptasensors for Biological and Chemical Analyte Detection. ELECTROANALYSIS. 2020 September . doi:10.1002/elan.202060388. Download

Melikov R, Srivastava SB, Karatum O, Dogru-Yuksel IB, Bahmani Jalali H, Sadeghi S, Dikbas UM, Ulgut B, Kavakli IH, Cetin AE, Nizamoglu S. Plasmon-Coupled Photocapacitor Neuromodulators.. ACS applied materials & interfaces. 2020 August ; 12 (32) : 35940-35949. doi:10.1021/acsami.0c09455. Download

Arif E. Cetin. Effect of Left handed Materials in Surface Plasmon Excitation and Propagation Length. Turkish Journal of Physics. 2019 February ; 43 : 26-36. doi:10.3906/fiz-1804-9. Download

Arif E. Cetin, and Seda Nur Topkaya. Photonic Crystal and Plasmonic Nanohole Based Label-Free Biodetection. Biosensors & Bioelectronics. 2019 May ; 132 : 196-202. doi:10.1016/j.bios.2019.02.047. Download

Seda Nur Topkaya, and Arif E. Cetin. Determination of Electrochemical Interaction Between 2‐(1H‐benzimidazol‐2‐yl) Phenol and DNA Sequences. ELECTROANALYSIS. 2019 August ; 31 (8) : 1554-1561. doi:10.1002/elan.201900199. Download

Habibe Durmaz, Arif E Cetin, Yuyu Li, and Roberto Paiella. A Polarization Insensitive Wide-Band Perfect Absorber. ADVANCED ENGINEERING MATERIALS. 2019 August ; 21 (8) : 1900188. doi:10.1002/adem.201900188. Download

Seda Nur Topkaya and Arif E. Cetin. Investigation of Metal Ion Effect on Specific DNA Sequences and DNA Hybridization. Electroanalysis. 2019 August ; 31 : 1-8. doi:10.1002/elan.201900391. Download

Arif E. Cetin, and Seda Nur Topkaya. Plasmonic Diffraction Field Pattern Imaging Could Resolve Ultra-Sensitive Bio-Information. ACS PHOTONICS. 2019 November ; 6 (11) : 2626-2635. doi:10.1021/acsphotonics.9b01076. Download

Yasa Eksioglu, Arif E. Cetin, and Habibe Durmaz. Multi-Band Plasmonic Platform Utilizing UT-Shaped Graphene Antenna Arrays. PLASMONICS. 2018 June ; 13 (3) : 1081–1088. doi:10.1007/s11468-017-0607-0. Download

Seda Nur Topkaya, Vasfiye Hazal Ozyurt, Arif E. Cetin, and Semih Otles. Nitration of Tyrosine and Its Effect on DNA Hybridization. BIOSENSORS & BIOELECTRONICS. 2018 April ; 102 : 464-469. doi:10.1016/j.bios.2017.11.061. Download

Arif E. Cetin, Pinar Iyidogan, Yuki Hayashi, Mark Wallen, Kandaswamy Vijayan, Eugene Tu, Mike Nguyen, and Arnold Oliphant. Plasmonic Sensor Could Enable Label-Free DNA Sequencing. ACS SENSORS. 2018 February ; 3 (3) : 561-568. doi:10.1021/acssensors.7b00957. Download

Habibe Durmaz, Yuyu Li, and Arif E. Cetin. A Multiple-Band Perfect Absorber for SEIRA Applications. Sensors and Actuators B: Chemical. 2018 December ; 275 : 174-179. doi:10.1016/j.snb.2018.08.053. Download

Ahmet F. Coskun, Seda Nur Topkaya, Ali K. Yetisen, and Arif E. Cetin. Portable Multiplex Optical Assays. Advanced Optical Materials. 2018 December ; 7 (4) : 1801109. doi:10.1002/adom.201801109. Download

Arif E. Cetin, Mark Stevens, Nicholas Calistri, Mariateresa Fulciniti, Selim Olcum, Robert Kimmerling, Nikhil Munshi, and Scott Manalis. Determining Therapeutic Susceptibility in Multiple Myeloma by Single-Cell Mass Accumulation. NATURE COMMUNICATIONS. 2017 November ; 8 (1613) : 1-12. doi:10.1038/s41467-017-01593-2. Download

Miquel Rudé, Vahagn Mkhitaryan, Arif E. Cetin, Timothy A. Miller, Albert Carrilero, Simon Wall, F. Javier García de Abajo, Hatice Altug, and Valerio Pruneri. Ultrafast and broadband tuning of resonant optical nanostructures using phase-change materials. ADVANCED OPTICAL MATERIALS. 2016 May ; 4 (7) : 1060-1066. doi:10.1002/adom.201600079. Download

Arif E. Cetin, Martin Drsata, Yasa Eksioglu, and Jiri Petracek. Extraordinary Transmission Characteristics of Subwavelength Nanoholes with Rectangular Lattice. PLASMONICS. 2016 June ; 12 (3) : 655-661. doi:10.1007/s11468-016-0311-5. Download

Arif E. Cetin, Semih Korkmaz, Habibe Durmaz, Ekin Aslan, Sabri Kaya, Roberto Paiella, and Mustafa Turkmen. Quantification of Multiple Molecular Finger-Prints by Dual-Resonant Perfect Absorber. ADVANCED OPTICAL MATERIALS. 2016 August ; 4 (8) : 1274-1280. doi:10.1002/adom.201600305. Download

Arif E. Cetin, Sabri Kaya, Alket Mertiri, Ekin Aslan, Shyamsunder Erramilli, Hatice Altug, and Mustafa Turkmen. Dual-Band Plasmonic Resonator based on Jerusalem Cross-Shaped Nanoapertures. PHOTONICS AND NANOSTRUCTURES-FUNDAMENTALS AND APPLICATIONS. 2015 June ; 15 : 73-80. doi:10.1016/j.photonics.2015.04.001. Download

Arif E. Cetin, Serap Aksu, Mustafa Turkmen, Dordaneh Etezadi, and Hatice Altug. Theoretical and Experimental Analysis of Subwavelength Bowtie-Shaped Antennas. JOURNAL OF ELECTROMAGNETIC WAVES AND APPLICATIONS. 2015 July ; 29 (13) : 1686-1698. doi:10.1080/09205071.2015.1051188. Download

Arif E. Cetin, Dordaneh Etezadi, Betty Galarreta, Mickael P. Busson, Yasa Eksioglu, and Hatice Altug. Plasmonic Nanohole Arrays on a Robust Hybrid Substrate for Highly Sensitive Label-Free Biosensing. ACS PHOTONICS. 2015 July ; 2 (8) : 1167-1174. doi:10.1021/acsphotonics.5b00242. Download

Yasa Eksioglu, Arif E. Cetin, and Jiri Petracek. Optical Response of Plasmonic Nanohole Arrays: Comparison of Square and Hexagonal Lattices. PLASMONICS. 2015 October ; 11 (3) : 851–856. doi:10.1007/s11468-015-0118-9. Download

Cihan Yilmaz, Arif E. Cetin, Georgia Goutzamanidis, Jun Huang, Sivasubramanian Somu, Hatice Altug, Dongguang Wei, and Ahmed Busnaina. “Three-dimensional Crystalline and Homogeneous Metallic Nanostructures Using Directed-Assembly of Nanoparticles. ACS NANO. 2014 April ; 8 (5) : 4547-4558. doi:10.1021/nn500084g. Download

Arif E. Cetin, Dordaneh Etezadi, and Hatice Altug. Accessible Nearfields by Nanoantennas on Nanopedestals for Ultrasensitive Vibrational Spectroscopy. ADVANCED OPTICAL MATERIALS. 2014 June ; 2 (9) : 866-872. doi:10.1002/adom.201400171. Download

Ahmet F. Coskun, Arif E. Cetin*, Betty C. Galarreta, Daniel Adrianzen Alvarez, Hatice Altug, and Aydogan Ozcan. Lensfree Optofluidic Plasmonic Sensor for Real-Time and Label-Free Monitoring of Molecular Binding Events over a Wide Field-of-Wiew. SCIENTIFIC REPORTS. 2014 October ; 4 (6789) : 1-7. doi:10.1038/srep06789. Download

Arif E. Cetin. FDTD Analysis of Optical Forces on Bowtie Antennas for High-Precision Trapping of Nanostructures. INTERNATIONAL NANO LETTERS. 2014 November ; 5 (1) : 21–27. doi:10.1007/s40089-014-0132-5. Download

Arif E. Cetin*, Mustafa Turkmen, Serap Aksu, Dordaneh Etezadi, and Hatice Altug. Multi-Resonant Compact Nanoaperture with Accessible Large Nearfields. APPLIED PHYSICS B-LASERS AND OPTICS. 2014 October ; 118 (1) : 29-38. doi:10.1007/s00340-014-5950-7. Download

Arif E. Cetin, Ahmet F. Coskun, Betty C. Galarreta, Min Huang, David Herman, Aydogan Ozcan, and Hatice Altug. Handheld High-Throughput Plasmonic Biosensor using Computational On-Chip Imaging. LIGHT-SCIENCE & APPLICATIONS. 2014 January ; 3 (e122) : 1-10. doi:10.1038/lsa.2014.3. Download

Serap Aksu, Arif E. Cetin, Ronen Adato, and Hatice Altug. Plasmonically Enhanced Vibrational Biospectroscopy Using Low-Cost Infrared Antenna Arrays by Nanostencil Lithography. ADVANCED OPTICAL MATERIALS. 2013 November ; 1 (11) : 798-803. doi:10.1002/adom.201300133. Download

Min Huang, Betty C. Galarreta, Arif E. Cetin, and Hatice Altug. Actively Transporting Virus Like Analytes with Optofluidics for Rapid and Ultrasensitive Biodetection. LAB ON A CHIP. 2013 September ; 13 (24) : 4841-4847. doi:10.1039/C3LC50814E. Download

Arif E. Cetin, Alket Mertiri, Shyamsunder Erramilli, and Hatice Altug. Thermal Tuning of Surface Plasmon Polaritons Using Liquid Crystal. ADVANCED OPTICAL MATERIALS. 2013 December ; 1 (12) : 915-920. doi:10.1002/adom.201300303. Download

Arif E. Cetin, Mustafa Turkmen, Serap Aksu, and Hatice Altug. Nanoparticle-Based Metamaterials as Multiband Plasmonic Resonator Antennas. IEEE TRANSACTIONS ON NANOTECHNOLOGY. 2012 January ; 11 (1) : 208 - 212. doi:10.1109/TNANO.2011.2174160. Download

Arif E. Cetin, Ahmet Ali Yanik, Alket Mertiri, Shyamsunder Erramilli, Ozgur E. Mustecaplioglu, and Hatice Altug. Field-Effect Active Plasmonics for Ultracompact Electro-Optic Switching. APPLIED PHYSICS LETTERS. 2012 September ; 101 (12) : 121113. doi:10.1063/1.4754139. Download

Arif E. Cetin, and Hatice Altug. Fano Resonant Ring/Disk Plasmonic Nanocavities on Conducting Substrates for Advanced Biosensing. ACS NANO. 2012 October ; 6 (11) : 9989-9995. doi:10.1021/nn303643w. Download

Ahmet Ali Yanik, Arif E. Cetin, Min Huang, Alp Artar, S. Hossein Mousavi, Alexander Khanikaev, John H. Connor, Gennady Shvets, and Hatice Altug. Seeing Protein Monolayers with Naked Eye Through Plasmonic Fano Resonances. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011 February ; 108 (29) : 11784-11789. doi:10.1073/pnas.1101910108. Download

Arif E. Cetin, Alp Artar, Mustafa Turkmen, Ahmet Ali Yanik, and Hatice Altug. Plasmon Induced Transparency in Cascaded π-Shaped Metamaterials. OPTICS EXPRESS. 2011 October ; 19 (23) : 22607-22618. doi:10.1364/OE.19.022607. Download

Arif E. Cetin, Ahmet Ali Yanik, Cihan Yilmaz, Sivasubramanian Somu, Ahmed Busnaina, and Hatice Altug. Monopole Antenna Arrays for Optical Trapping, Spectroscopy, and Sensing. APPLIED PHYSICS LETTERS. 2011 February ; 98 (111110) : 1-3. doi:10.1063/1.3559620. Download

Mustafa Turkmen, Serap Aksu, Arif E. Cetin, Ahmet Ali Yanik, and Hatice Altug. Multi-Resonant Metamaterials Based on UT-Shaped Nano-Aperture Antenna. OPTICS EXPRESS. 2011 April ; 19 (8) : 7921-7928. doi:10.1364/OE.19.007921. Download

Arif E. Cetin, Alphan Sennaroglu, and Ozgur E. Mustecaplioglu. Nanoscale plasmonic devices for dynamically controllable beam focusing and scanning. PHOTONICS AND NANOSTRUCTURES-FUNDAMENTALS AND APPLICATIONS. 2010 January ; 8 (1) : 7-13. doi:10.1016/j.photonics.2009.12.001. Download

Arif E. Cetin, and Ozgur E. Mustecaplioglu. Electrically tunable Dicke effect in a double-ring resonator. PHYSICAL REVIEW A. 2010 April ; 81 (4) : 043812. doi:10.1103/PhysRevA.81.043812. Download

Arif E. Cetin, K. Guven, and Ozgur E. Mustecaplioglu. Active Control of Focal Length and Beam Deflection in a Metallic Nano-Rod Lens System with Multiple Sources. OPTICS LETTERS. 2010 June ; 35 (12) : 1980-1982. doi:10.1364/OL.35.001980. Download

Total : 67

Selected Book Chapters

Overcoming Mass-Transport Limitations with Optofluidic Plasmonic Biosensors and Particle Trapping (2012). Optochemical Nanosensors. Taylor and Francis.

Total : 1

Selected Proceedings

Fatma Kurul, Meryem Beyza, Furkan Kocer, H. Bertan Acar, Seda Nur Topkaya, Arif E. Cetin 2024, 'Revolutionizing cell-based analyses: An electrochemical analysis platform with integrated incubator capabilities', IFCC WorldLab Dubai 2024, Dubai, UAE, May 26, 2024 .

Meryem Beyza Avci, Fatma Kurul, S. Deniz Yasar, Arif E. Cetin 2024, 'Cell counting platform for life science applications', SPIE Photonics Europe, Strasbourg, France, April 11, 2024 .

Fatma Kurul, Meryem Beyza Avci, Sena Yaman, Seda Nur Topkaya, and Arif E. Cetin 2024, 'Portable optofluidic device for dynamic binding analysis in field-settings', SPIE Photonics Europe, Strasbourg, France, April 11, 2024 .

Meryem B. Avci, Sevim D. Yasar, and Arif E. Cetin, 2024, 'Advancing cellular analyses through a fully automated imaging-based liquid handling platform', SPIE Photonics Europe, Strasbourg, France, April 11, 2024 .

Meryem Beyza Avci, Seda Nur Topkaya, Ozden Yalcin-Ozuysal, Ali Khademhosseini, Arif E. Cetin 2023, 'Plasmonic functional assay platform for measuring single cell growth through refractive index sensing', European Conferences on Biomedical Optics, Munich, June 20, 2023 .

Fatma Kurul, Ziya Ata Yazici, Zeynep A. Kocer, Seda Nur Topkaya, Arif E. Cetin 2023, 'Low-cost and portable plasmonic biosensor for label-free detection of viruses in resource-limited settings', European Conferences on Biomedical Optics, Munich, June 20, 2023 .

Zeynep Ovgu Yayci, Ugur Dura, Zeynep Betul Kaya, Arif E.Cetin, Mehmet Turkan 2022, 'Microscale image enhancement via PCA and well-exposedness maps', IEEE International Conference Image Processing (IEEE-ICIP), France, Oct. 16, 2022 .

Yasa Eksioglu and Arif E. Cetin 2017, 'Investigation of plasmonic transmission in UT shaped graphene arrays', SPIE Optics + Optoelectronics, Prague, Czech Republic, May 16, 2017 .

Arif E. Cetin, Martin Drsata, Yasa Eksioglu, and Jiri Petracek 2016, 'Effect of Lattice Geometry on Optical Transmission through Subwavelength Nanohole Arrays', MetaMaterials, Chania, Greece, Nov. 17, 2016 .

Dordaneh Etezadi, Arif E. Cetin, and Hatice Altug 2015, 'Plasmonic Nanoantennas on Nanopedestals for Ultra-Sensitive Vibrational IR-Spectroscopy', CLEO 2015, San Jose, CA, USA, May 11, 2015 .

Ahmet F. Coskun, Arif E. Cetin, Betty, C. Galarreta, Daniel A. Alvarez, Hatice Altug, and Aydogan Ozcan 2015, 'Field-Portable Optofluidic Plasmonic Biosensor for Wide-Field and Label-Free Monitoring of Molecular Interactions', CLEO 2015, San Jose, CA, USA, May 11, 2015 .

Arif E. Cetin, Ahmet F. Coskun, Betty, C. Galarreta, Min Huang, David Herman, Aydogan Ozcan, and Hatice Altug 2014, 'Hand-held Plasmonic Biosensor for High-Throughput Sensing for Point-of-Care Applications', CLEO 2014, San Jose, CA, USA, June 9, 2014 .

Arif E. Cetin, Alket Mertiri, Min Huang, Shyamsunder Erramilli, and Hatice Altug 2014, 'Dynamic Tuning of Surface Plasmon Polaritons via Thermally Controlled Liquid Crystals', CLEO 2014, San Jose, CA, USA, June 9, 2014 .

Hatice Altug, Arif E. Cetin, Ahmet F. Coskun, Betty, C. Galarreta, Min Huang, David Herman, and Aydogan Ozcan 2014, 'Hand-Held and High-Throughput Biosensor with Plasmonics and Lens-Free Imaging', Latin America Optics and Photonics Conference, Cancun, Mexico, Nov. 17, 2014 .

Min Huang, Betty, C. Galarreta, Arif E. Cetin, and Hatice Altug 2014, 'Effective Delivery of Analytes with Optofluidics for Ultrasensitive Biodetection', CLEO 2014, San Jose, Jan. 12, 2014 .

Hatice Altug, Min Huang, and Arif E. Cetin 2013, 'High-Throughput and Low-Cost Nanophotonic Based Diagnostics Technologies', 2013 Transducers + Eurosensors XXVII: The 17th International Conference, Barcelona, Spain, June 17, 2013 .

Arif E. Cetin, and Hatice Altug 2013, 'Asymmetric Ring/Disk Nanocavities on Conducting Substrates for Strong Fano-Interference', CLEO 2013, San Jose, CA, USA, June 10, 2013 .

Arif E. Cetin, Cihan Yilmaz, Ahmet Yanik, Sivasubramanian Somu, Ahmed Busnaina, and Hatice Altug 2012, 'Optical trapping, biosensing, and spectroscopy in a single plasmonic platform', MRS Fall Meeting, Boston, MA, USA, Jan. 12, 2012 .

Arif E. Cetin, Alp Artar, Mustafa Turkmen, Ahmet Ali Yanik, and Hatice Altug 2012, 'Plasmon Induced Transparency in Cascaded π-Shaped Structures', SPIE Optics + Photonics, San Diego, CA, USA, Oct. 15, 2012 .

Arif E. Cetin, Alp Artar, Mustafa Turkmen, Ahmet Ali Yanik, and Hatice Altug 2012, 'Plasmon induced transparency with asymmetric π-shaped metamaterials', CLEO 2012, San Jose, CA, USA, May 7, 2012 .

Hatice Altug, Ahmet Ali Yanik, Arif E. Cetin, Alp Artar, and Min Huang 2012, 'Metamaterials, plasmonics, and nanofluidics for ultrasensitive spectroscopy and bio-detection', Optical Sensors, Toronto, Canada, June 12, 2012 .

Arif E. Cetin, Ahmet Ali Yanik, Cihan Yilmaz, Sivasubramanian Somu, Ahmed Busnaina, and Hatice Altug 2011, 'Plasmonic Monopole Antenna Arrays for Biosensing, Spectroscopy and nm-Precision Optical Trapping', CLEO 2011, Baltimore, MD, USA, May 2, 2011 .

Mustafa Turkmen, Serap Aksu, Arif E. Cetin, Ahmet Ali Yanik, Alp Artar, and Hatice Altug 2011, 'U-Shaped Nano-Apertures for Enhanced Optical Transmission and Resolution', SPIE Optics + Photonics, Orlando, FL, USA, May 2, 2011 .

Arif E. Cetin, Ahmet Ali Yanik, Cihan Yilmaz, Sivasubramanian Somu, Ahmed Busnaina, and Hatice Altug 2011, 'Plasmonic nanopillar arrays for optical trapping, biosensing, and spectroscopy', SPIE Optics + Photonics, San Diego, CA, USA, Sept. 1, 2011 .

Mustafa Turkmen, Serap Aksu, Arif E. Cetin, Ahmet Ali Yanik, and Hatice Altug 2011, 'Optical properties of UT-shaped plasmonic nanoaperture antennas', SPIE Optics + Photonics, San Diego, CA, USA, Sept. 1, 2011 .

Mustafa Turkmen, Serap Aksu, Arif E. Cetin, Ahmet Ali Yanik, and Hatice Altug 2011, 'Compact and multi-resonant plasmonic metamaterials based on nano-apertures', General Assembly and Scientific Symposium (2011 XXXth URSI), Istanbul, Turkey, Aug. 15, 2011 .

Hatice Altug, Ahmet Ali Yanik, Ronen Adato, Min Huang, Alp Artar, Serap Aksu, and Arif E. Cetin 2011, 'Integrated Plasmonic Systems for Ultrasensitive Spectroscopy and Biodetection', General Assembly and Scientific Symposium (2011 XXXth URSI), Istanbul, Turkey, Aug. 15, 2011 .

Arif E. Cetin, Cihan Yilmaz, Ahmet Ali Yanik, Sivasubramanian Somu, Ahmed Busnaina, and Hatice Altug 2011, 'Optical Trapping and Manipulation with Plasmonic Nanopillar Antennas for Enhanced Biosensing', FiO 2011, San Jose, CA, USA, Oct. 14, 2011 .

Ahmet Ali Yanik, Arif E. Cetin, Min Huang, Alp Artar, Hossein Mousavi, Alexander Khanikaev, John H. Connor, Gennady Shvets, and Hatice Altug 2011, 'Ultrasensitive Label Free Biosensors Enables Seeing Protein Monolayers with The Naked Eye', FiO 2011, San Jose, CA, USA, Oct. 14, 2011 .

Ahmet Ali Yanik, Arif E. Cetin, Min Huang, Alp Artar, Hossein Mousavi, Alexander Khanikaev, John H. Connor, Gennady Shvets, and Hatice Altug 2011, 'Ultrasensitive plasmonic Fano sensor enables seeing protein monolayers with naked eye', IEEE Photonics Conference, Arlington, VA, USA, Oct. 10, 2011 .

Hatice Altug, Alp Artar, Serap Aksu, Min Huang, Ahmet Ali Yanik, and Arif E. Cetin 2011, 'Plasmon enhanced detectors for smart lighting applications', IEEE Photonics Conference, Arlington, VA, USA, Oct. 10, 2011 .

Arif E. Cetin, and Ozgur E. Mustecaplioglu 2009, 'Effects of Bloch’s Hydrodynamic Model on Surface Plasmon Polariton Dispersion Curve and Enhanced Transmission of Light through Single Nano-Apertures', SPIE Symposium of Microtechnologies for the New Millennium, Dresden, Germany, April 1, 2009 .

Total : 32

Patents

  • Arif E. Cetin 2022 , Portable Incubator Platform Integrated Into A Portable Imaging Device, US Patent App. 17/639,916
  • Arif E. Cetin, Idil Karaca Acari, Seda Nur Topkaya Cetin, Burhan Ates, Suleyman Koytepe, Turgay Seckin, Sevket Erbil Unsal, Balahan Makay, Ceyhun Acari, Ismet Yılmaz 2022 , FMF (Ailevi Akdeniz Ateşi) Hastalığı Tanısı İçin Biyosensör Sistemi, None
  • Arif Engin Cetin 2021 , Plasmonic Cell-Mass Accumulation Profiling Platform for Determining Therapeutic Responses of Cancer Cells, WO/2022/119530
  • Arif Engin Cetin 2020 , Kanser Hücrelerinin Terapötik Yanıtlarını Saptamaya Yönelik Plazmonik Hücre Kütle Birikim Profili Belirleme Platformu, TR 2020/19537
  • Arif Engin Cetin 2020 , A Portable Incubator Platform Integrated Into A Portable Imaging Device, WO/2021/050023
  • Hatice Altug, and Arif E. Cetin 2019 , Plasmonic nanohole arrays on hybrid substrate for highly sensitive label-free biosensing, US10436711B2
  • Arif Engin Cetin 2019 , Taşınabilir Bir Görüntüleme Cihazina Entegre Edilmiş Taşinabilir Bir İnkübatör Platformu, None
  • Arif E. Cetin , Automated, Imaging-Based, Five-Axis Liquid Handler, None
  • Arif E. Cetin, Seda Nur Topkaya , Incubator Integrated Electrochemical Analysis Platform, None

Awards

  • 2210-D Graduate Scholarship Program for Domestic Industry (Damla AYDOĞAN) by TUBITAK, 2024
  • 2210-D Graduate Scholarship Program for Domestic Industry (Meryem Beyza AVCI) by TUBITAK, 2023
  • TOYP-International Finalist, Ten Outstanding Young Persons of the World Program by Junior Chamber International (JSI), 2023
  • Doktorclub Awards, Finalist in the Innovative Healthcare Professional / Healthcare Professional of the Year Awards by Doktorclub, 2023
  • Dr. Aysun-Ahmet Küçükel Medicine Awards, Best Scientific Research Award, by Guven Education and Health Foundation, 2022
  • Best Poster Competition Third Prize (Hezzal KÜÇÜKSELBES) by Ulusal Optik, Elektro-Optik ve Fotonik Çalıştayı’nda (FOTONİK 2022), 2022
  • Artificial Intelligence in Health Contest, Best Presentation Award (Fatma KURUL) by TEKNOFEST, 2022
  • Artificial Intelligence in Health Contest, Special Jury Award (Fatma KURUL) by TEKNOFEST, 2022
  • 2210-D Graduate Scholarship Program for Domestic Industry (Fatma KURUL) by TUBITAK, 2022
  • ERASMUS + Internship Mobility Grant, Technical University of Munich (Fatma KURUL) by Technical University of Munich, 2022
  • Digital Technologies in Industry Contest Finalist (Meryem Beyza AVCI, Fatma KURUL and Hezzal KUCUKSELBES) by TEKNOFEST, 2022
  • 3rd place in Society and Health Category by Genç Beyinler Yeni Fikirler, 2022
  • TUBITAK 2242 Health Category Finalist (Ugur DURA, Zeynep Ovgu YAYCI, Zeynep Betul KAYA) by TUBITAK, 2022
  • Turkish Academy of Sciences - Outstanding Young Scientists Awards (TÜBA-GEBİP) by Turkish Academy of Sciences (TÜBA), 2022
  • TOYP-Turkey Winner, Turkey's 10 Successful Young People Program, Science and Technical Development Category, TOYP = Ten Outstanding Young Persons of the World Program (Turkey Branch) by Junior Chamber International (JSI). by JSI, 2022
  • Sedat Simavi Awards, Health Sciences Category, Turkish Journalists Association by Türkiye Gazeteciler Cemiyeti, 2022
  • TTGV Awards - Refik Üreyen Leadership Stories in R&D Organizations Award by Türkiye Teknoloji Geliştirme Vakfı, 2022
  • Ocean Insight 2020-21 Grant Program, The Inspiration Award by Ocean Insight, 2021
  • Young Scientist Awards by The Science Heroes Association, 2021
  • TUBITAK Incentive Award by TUBITAK, 2021
  • Biotechnology Innovation Competition 2nd Place (Fatma KURUL) by TEKNOFEST, 2021
  • TUSEB Aziz Sancar Incentive Award by TUSEB (Health Institutes of Turkey), 2020
  • Doktorclub Awards, Finalist in the Biotechnology and Genome Technology, R&D / Innovation Application of the Year by Doktorclub, 2020
  • Young Scientist (BAGEP) Award by Science Academy, 2019
  • TUBITAK Career Integration Fellowship (2232) by TUBITAK, 2018
  • Koch Institute Quinquennial Cancer Research Fellowship by Massachusetts Institute of Technology, 2016
  • EUROPT(R)ODE XII Conference Best Poster Award by EUROPT(R)ODE, 2014
  • Boston University, Center for Nanoscience & Nanobiotechnology Award by Boston University, 2011
  • Boston University, Photonics Center Junior Fellowship by Boston University, 2009
  • TUBITAK (The Scientific and Technological Research Institution of Turkey) Travel Award (Code: 2224-A) by TUBITAK, 2008
  • TUBITAK Graduate Fellowship (Code: 2228-A) by TUBITAK, 2007
  • Koc University, Vehbi Koc Scholarship (5-year) by Koc University, 2002

Academic Memberships

  • Optical Society of America (OSA), 2011
  • The International Society for Optical Engineering (SPIE), 2011
  • Materials Research Society (MRS), 2012
  • The Science Academy, Turkey, 2019
  • TÜBA-Turkish Academy Of Science, 2022
  • Technology Development Foundation of Turkey (TTGV), 2022

Contact

Cetin Lab. on Nanophotonics and Biodetection Systems

Research Group Leader

Arif Engin ÇETİN
arifengin.cetin@ibg.edu.tr
+90 232 299 41 00 (5161)
 +9 0 (232) 299 41 66