TÜBİTAK backs growth phenotype study
The project titled “Investigation of the Relationship Between the Large Phenotype Induced by miR-124-3p Microinjection and Genomic Imprinting via the miR-124-3p/Sp1/Dnmt1 Axis Through Whole Genome Methylation Analysis”, led by Dr. Keziban Korkmaz Bayram, a researcher at the IBG Gene Targeting and Transgenic Models Platform, has been awarded support under the TÜBİTAK 3501 - Career Development Program.
The project team includes Dr. Arslan Bayram, Dr. Ali Tuğrul Akın, and Dr. Kerem Esmen as researchers, with Dr. Minoo Rassoulzadegan, Prof. Uğur Özbek, Prof. Şerif Şentürk, and Prof. Kasım Diril contributing as advisors.
The project aims to uncover the epigenetic mechanisms underlying the cellular overgrowth phenotype. In this context, it will systematically investigate the regulatory dynamics of gene expression to determine which genes are silenced and which are aberrantly overexpressed.