Group Members

Angelov Lab. on Chromatin and Repair

Research Group Leader

+90 232 299 41 00 (None)

Helin SAĞIR PhD Student

Tuğçe BATUR Researcher

Imtiaz Nisar LONE Researcher

Ece Şule ZANGUR MSc Student

Former Members

Serhan TURUNÇ PhD Student


Khalid ABDALLA Researcher

Selected Publications

Abu Alhaija AA, Lone IN, Ozkuru Sekeroglu E, Batur T, Angelov D, Dimitrov S, Hamiche A, Firat Karalar EN, Ercan ME, Yagci T, Alotaibi H, Diril MK. Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1-4.. FEBS open bio. 2023 December . doi:10.1002/2211-5463.13750. Download

Cadet J, Angelov D, Wagner JR. Hydroxyl radical is predominantly involved in oxidatively generated base damage to cellular DNA exposed to ionizing radiation.. International journal of radiation biology. 2022 May : 1-7. doi:10.1080/09553002.2022.2067363. Download

Angelov D, Lone IN, Menoni H, Cadet J. Interstrand Crosslinking Involving Guanine: A New Major UVC Laser-Induced Biphotonic Oxidatively Generated DNA Damage.. Photochemistry and photobiology. 2022 May ; 98 (3) : 662-670. doi:10.1111/php.13587. Download

Boopathi R, Danev R, Khoshouei M, Kale S, Nahata S, Ramos L, Angelov D, Dimitrov S, Hamiche A, Petosa C, Bednar J. Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends.. Nucleic acids research. 2020 June ; 48 (10) : 5735-5748. doi:10.1093/nar/gkaa246. Download

Shukla, MS; Syed, SH; Boopathi, R; Ben Simon, E; Nahata, S; Ramos, L; Dalkara, D; Moskalenko, C; Travers, A; Angelov, D; Dimitrov, S; Hamiche, A; Bednar, J. Generation of Remosomes by the SWI/SNF Chromatin Remodeler Family. Scientific Reports. 2019 October ; 9 . doi:10.1038/s41598-019-50572-8. Download

Cadet J, Wagner JR, Angelov D. Biphotonic Ionization of DNA: From Model Studies to Cell. Photochemistry and Photobiology. 2019 January ; 95 (1) : 59-72. doi:10.1111/php.13042. Download

Torben Schindler, Adrián González, Ramachandran Boopathi, Marta Marty Roda, Lorena Romero-Santacreu, Andrew Wildes, Lionel Porcar, Anne Martel, Nikos Theodorakopoulos, Santiago Cuesta-López, Dimitar Angelov, Tobias Unruh, and Michel Peyrard. Kinky DNA in solution: Small-angle-scattering study of a nucleosome positioning sequence. Phys Rev E. 2018 October ; 98 : 04241. doi:10.1103/PhysRevE.98.042417. Download

I. Garcia-Saez, H. Menoni, R. Boopathi, M. S. Shukla, L. Soueidan, M. Noirclerc-Savoye, A. Le Roy, D. A. Skoufias, J. Bednar, A. Hamiche, D. Angelov¶, C. Petosa¶, S. Dimitrov¶. Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation. Mol Cell. 2018 December ; 72 (5) : 902-912 E7. doi:10.1016/j.molcel.2018.09.027. Download

Bednar J, Garcia-Saez I, Boopathi R, Cutter AR, Papai G, Reymer A, Syed SH, Lone IN, Tonchev O, Crucifix C, Menoni H, Papin C, Skoufias DA, Kurumizaka H, Lavery R, Hamiche A, Hayes JJ, Schultz P, Angelov D, Petosa C, Dimitrov S. Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.. Molecular cell. 2017 May ; 66 (3) : 384-397.e8. doi:10.1016/j.molcel.2017.04.012. Download

Menoni H, Di Mascio P, Cadet J, Dimitrov S, Angelov D. Chromatin associated mechanisms in base excision repair - nucleosome remodeling and DNA transcription, two key players.. Free radical biology & medicine. 2017 June ; 107 : 159-169. doi:10.1016/j.freeradbiomed.2016.12.026. Download

Roulland Y, Ouararhni K, Naidenov M, Ramos L, Shuaib M, Syed SH, Lone IN, Boopathi R, Fontaine E, Papai G, Tachiwana H, Gautier T, Skoufias D, Padmanabhan K, Bednar J, Kurumizaka H, Schultz P, Angelov D, Hamiche A, Dimitrov S. The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity.. Molecular cell. 2016 August ; 63 (4) : 674-685. doi:10.1016/j.molcel.2016.06.023. Download

Lahmy S, Pontier D, Bies-Etheve N, Laudié M, Feng S, Jobet E, Hale CJ, Cooke R, Hakimi MA, Angelov D, Jacobsen SE, Lagrange T. Evidence for ARGONAUTE4-DNA interactions in RNA-directed DNA methylation in plants.. Genes & development. 2016 December ; 30 (23) : 2565-2570. doi:10.1101/gad.289553.116. Download

Charles Richard JL, Shukla MS, Menoni H, Ouararhni K, Lone IN, Roulland Y, Papin C, Ben Simon E, Kundu T, Hamiche A, Angelov D, Dimitrov S. FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC.. PLoS genetics. 2016 July ; 12 (7) : e1006221. doi:10.1371/journal.pgen.1006221. Download

Total : 13


The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Repair of DNA Damage in Rahman Syndrome, Ongoing

The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Mechanism of Linker Histone H1-Mediated Chromatin Folding Under Normal and Diseases Conditions, Ongoing

The Scientific and Technological Research Council of Turkey - TUBITAK - RD : Sağlıkta ve Rahman Sendromunda Bağlayıcı Histon H1E, Ongoing


Angelov Lab. on Chromatin and Repair

Research Group Leader

+90 232 299 41 00 (None)