Vivarium Unit

İBG-Vivaryum Rodent Unit

IBG Vivarium is a service unit that provides high-standard in vivo model support for studies in various fields of biotechnology, including regenerative medicine, cancer research, drug screening, and artificial organ development. Serving both internal and external researchers, IBG Vivarium also contributes directly to research projects.

IBG Vivarium holds all necessary legal permits for the production, use, and supply of mouse, rat, rabbit, guinea pig, hamster, and gerbil species. It is also one of the few authorized centers in the country permitted to conduct research on genetically modified organisms (GMOs). Covering a closed area of 2,700 m², the vivarium has the infrastructure to accommodate up to 7,000 animals, enabling large-scale experimental studies.

In our facility, animal welfare and physiological needs are prioritized in the housing and care of laboratory animals. All experimental procedures are conducted under isolated and controlled microenvironmental conditions. Our laboratory is equipped with both individually ventilated cages (IVC) systems and conventional cages, ensuring a standardised, healthy microenvironment for each animal.

With our advanced infrastructure and expertise, we provide strong support to scientific research at every stage of the preclinical process.

Services and Research Areas 

Laboratory Animal Services

• Housing, care, and procedures in accordance with animal welfare and ethical principles
• Housing in specific pathogen-free (SPF) conditions
• Management of special mouse and rat colonies such as NSG, nude, Balb/c, C57BL/6, etc.
• Inhalation anesthesia applications, experiment monitoring, data collection, and obtaining quantitative measurements
• Basic intervention services such as experimental surgery, injection, blood collection, and sample collection

Drug and Vaccine Efficacy Testing

• Efficacy and safety analysis of newly developed drug molecules and vaccines
• Bioavailability, biodistribution, and bioequivalence studies
• Dose-response relationship and optimization of treatment duration

Cancer Modeling

• Subcutaneous and orthotopic tumor models (xenograft, syngeneic, etc.)
• Efficacy studies on chemotherapy, immunotherapy, and targeted therapies
• Tumor progression, metastasis, and survival analyses
• Studies using NSG, nude, and other immunodeficient models

Pharmacology and Toxicology Testing

• Acute, subacute, and chronic toxicity tests
• Organ toxicity, hematological, and biochemical analyses
• Pharmacokinetic (PK) and pharmacodynamic (PD) studies

Disease Modeling (BSL-1)

• Infection and inflammation models at BSL-1 level
• Modeling of autoimmune, metabolic, neurological, and respiratory diseases
• Disease-specific treatment and prophylaxis experiments

Efficacy and Mechanism Studies

• Evaluation of in vivo efficacy of drugs or biological agents
• Experiments supported by immune response, histopathology, and molecular analyses
• Combination therapy protocols and comparative analyses

Tissue and Biological Material Collection

• Collection of blood, tissue, organs, and biological fluids under standardized conditions
• Preparation of FFPE, fresh tissue, and frozen samples
• Provision of suitable biological samples for molecular analyses

Training Services

• Organizing training for scientists conducting or planning to conduct research with laboratory animals

Scientific Consultancy Services