Zebrafish Facility
Zebrafish Facility (Aquatic Vertebrate Experimental Animal Unit)
Zebrafish (Danio rerio) is a small vertebrate experimental model widely used in basic, translational, and biopharmaceutical research. The İBG Zebrafish Facility has been operating since 2016 and is one of the leading laboratories in Türkiye. Our unit provides infrastructure and technical support that comply with national and international standards, ensure hygienic conditions, and implement advanced technologies, offering these resources to researchers and the private sector.
About Zebrafish
Due to its high genetic similarity to humans and the conservation of functional characteristics of organs and organ systems, zebrafish is an effective model for translational research. Using genome-editing tools and transgenic technologies, experimental models can be generated for biological processes and diseases of interest. In addition, chimeric animals and xenograft cancer models can be established by transplanting human cells into zebrafish. Zebrafish stands out as a practical and efficient model for ecotoxicology and drug toxicology tests at both adult and larval stages. It is well suited for modeling genetic diseases, drug testing, and mechanistic studies using gene-editing tools.
About the Facility
The İBG Zebrafish Facility and laboratories are among the most advanced and well-equipped zebrafish facilities in Türkiye. With a large housing capacity and state-of-the-art equipment, it offers an ideal working environment for both internal and external researchers involved in zebrafish-based research projects.
The unit provides technical infrastructure and support services enabling fish housing in automated systems, production of transgenic and mutant fish via microinjection systems, and live imaging using fluorescent and color cameras.
Our expert team is responsible for the daily care of all fish in the facility. The breeding, feeding, rearing, and health monitoring of all fish strains are fully carried out by the unit staff.
Our facility houses transgenic reporter, wild-type, and mutant strains.
Support is also provided for project-specific business development and project consultancy processes. In this context, services are offered to internal and external researchers as well as the private sector in areas such as the generation of disease models, development of mutant fish, and establishment of transgenic lines.
Follow-up services are also provided for the import or transfer of zebrafish strains from abroad or from other institutions within the country.
The İBG Zebrafish Facility is open to all stakeholders who wish to use zebrafish models. If you would like to use fish models in your project or business processes, please contact us to benefit from our standard services or from customized consultancy services and applications tailored to your project.
Research conducted in our facility has been published in international high–impact factor journals.
For more information about our research and collaboration opportunities, please contact us at: zf(@)ibg.edu.tr, gulcin.cakan(@)ibg.edu.tr
Our Team
Gülçin Çakan Akdoğan (Facility Director, Genetik Expert)
Emine Gelinci (Expert Facility Manager)
Günay Atılkan (Care Giver, Support Personnel)
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Equipment
Camera-equipped stereo microscope Olympus SZX10 (SC50 camera)
Camera-equipped fluorescence stereo microscope Olympus SZX16 (XC50 camera)
Fluorescence stereo microscope Olympus SZX10
Stereo microscope with transmitted illumination Zeiss Stemi 508
Microinjection systems (WPI PicoPump, Narishige micromanipulator)
Needle puller (Sutter) microscopes
Behavioral experiment room
Our Services
|
Services |
Academic User Suggested Price (TL)* |
Private Sector Suggested Price (TL) |
|
Zebrafish Facility Management – Basic Training |
19000 |
28000 |
|
Zebrafish Facility Management – Advanced Training |
32000 |
45000 |
|
Training: Xenograft Injection and Analysis |
6500 |
9500 |
|
Training: Microinjection Technique |
6500 |
8000 |
|
Zebrafish (WT / Adult) Sale (for experimental use) |
200 |
250 |
|
Zebrafish (WT / Adult) Breeding Stock Sale |
450 |
600 |
|
Zebrafish (Transgenic / Adult) Sale (for experimental use) |
400 |
500 |
|
Zebrafish (Transgenic / Adult) Breeding Stock Sale |
900 |
1200 |
|
Zebrafish Embryo Sale (Live, 50 embryos) |
450 |
499 |
|
Zebrafish Embryo Sale (Fixed, 50 embryos) |
500 |
699 |
|
Use of Camera-equipped Stereo Microscope (per hour) |
230 |
400 |
|
Use of Micromanipulation System (per hour) |
225 |
300 |
|
Use of Camera-equipped Fluorescence Microscope (per hour) |
340 |
500 |
|
Toxicology Analysis (priced per compound) |
6800 |
9500 |
|
Zebrafish Housing (per tank / per day) |
16 |
30 |
|
Use of Breeding Fish (weekly access) |
300 |
600 |
|
Zebrafish Embryo Production (WT) for Experimental Use (per embryo) |
5 |
8 |
|
Zebrafish Embryo Production (Transgenic) for Experimental Use (per embryo) |
7 |
12 |
|
Surgical Procedures (necroscopy, etc.) (per procedure) |
450 |
500 |
|
Injection (Xenograft) (per injection) |
11 |
16 |
|
Xenograft Experiment Outcome Analysis (priced per experimental group) |
4500 |
9000 |
|
Zebrafish Fixation (Live) (per embryo/larva) |
55 |
70 |
|
Zebrafish Fixation (Fixed) (per embryo/larva) |
35 |
50 |
|
In Vitro Fertilization (IVF) |
800 |
1600 |
|
Transgenic Zebrafish Line Development |
Project-based pricing |
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CRISPR/Cas9-mediated Mutant Zebrafish Development |
Project-based pricing |
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Nanocarrier System / Exosome Toxicity Testing |
PProject-based pricing |
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Nanocarrier System / Exosome Validation Testing |
Project-based pricing |
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Project / Business Development Consultancy (hourly rate) |
5000 |
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Zebrafish Import Process Management (per shipment package) |
Costs + 5000 TL |
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*Discounted rates will be applied to İBG and DEU employes.
Courses
Experimental Animal Use Certificate Courses
In our courses organized in collaboration with the IBG-HADYEK and the IBG Zebrafish unit, you can obtain the certificate required to conduct zebrafish studies. As part of our course's practical applications, we teach our trainees all the basic procedures, including microinjection, mating, anesthesia, euthanasia, necropsy, and sample collection..
https://ibg.edu.tr/izmir-biyotip-ve-genom-merkezi-deney-hayvanlari-kullanimi-kursu-2025
Model Courses
Model courses are also organized within our unit. The international support-funded ICGEB "Training on Latest Technologies in Genome Editing and Assisted Reproductive Techniques" was successfully completed within 2025.
https://ibg.edu.tr/genom-duzenleme-ve-yardimci-ureme-tekniklerindeki-en-yeni-teknolojiler-egitimi2
You can submit your training requests thru our social media accounts and via email: @cakanzebrafishlab (Instagram), zf@ibg.edu.tr,
