Projects and Patents

Projects

TÜBİTAK 1004: Target-Specific Pan-Cancer Therapies (PAN-TER), Ongoing

TÜBİTAK 1001: Development of Pichia pastoris strains for industrial-scale biopharmaceutical production via metabolic engineering, Ongoing

TÜBİTAK 1004: Development of a Recombinant Protein-Based Vaccine Against SARS-CoV-2, Completed

TÜBİTAK 1004: Development of “Ghost Receptor-Antibody” Based Drugs Against SARS-CoV-2, Completed

TÜBİTAK 1007: Development and production of biosimilar products containing monoclonal antibodies or antibody fragments, Completed

Patents

Inan, M., Karaoğlan, M. and Erden Karaoğlan, F. 2023.Determination of regulatory DNA regions of Alcohol Dehydrogenase 3 (ADH3) Promoter and Design of synthetic promoters for recombinant protein production. US11,643,663B2

Danielle Marie Mitchell, Leon F. Garcia-Martinez, Patricia Dianne McNeill, Ethan Wayne Ojala, Mehmet Inan,John Latham 2022. Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris, US11225667B2

Mitchell, D.M., Garcia-Martinez, L.F., McNeill, P.D., Ojala, E.W., Inan, M. and Latham, J. 2018 , Multi-copystrategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris, US10150968B2

Mehmet İNAN 2010 , PiPichia pastoris PIR1 secretion signal peptide for recombinant protein expression and Pichia pastoris PIR1 and PIR2 anchor domain peptides for recombinant surface display, US7741075B2

Mehmet Inan, Michael M. Meagher Andrew K. Benson 2004. Alcohol oxidase 1 regulatory nucleotide sequences for heterologous gene expression in yeast, US6699691B2