Services and Research Areas

• Molecule Discovery and Cloning
• Antibody discovery, vector design, codon optimization, B cell isolation, and antibody sequence acquisition
• Cell Line Development
• Escherichia coli
• Pichia pastoris
• CHO (Chinese Hamster Ovary) & HEK293
• Upstream Process Development
• Media optimization
• Process optimization
• Bioreactor scaling: from 96-well plate, shake flask → 7 L
• Pilot production: 50–200 L
• Downstream Process Development
• Chromatographic purification: capture and polishing steps
• Membrane-assisted purification: ultrafiltration/diafiltration (UF/DF)
• Virus inactivation and filtration
• Analytical and Functional Characterization
• Chemical and physicochemical analyses: HPLC, UPLC, SDS-PAGE
• Structural analyses: DSC (thermal stability), SPR (antigen & Fc binding)
• Biological assays: ELISA, Fc receptor interaction tests