Scientific Publications - 2016

IBG Affiliated : 34; * Current Adress IBG :5

Calibasi Kocal G, Güven S, Foygel K, Goldman A, Chen P, Sengupta S, Paulmurugan R, Baskin Y, Demirci U. Dynamic Microenvironment Induces Phenotypic Plasticity of Esophageal Cancer Cells Under Flow. Scientific reports. 2016 December; 6: 38221. doi:10.1038/srep38221.

Diler, Ebru; Unver, Turgay; Karakulah, Gokhan. Differential Expression of Hyperhydricity Responsive Peach MicroRNAs. JOURNAL OF INTEGRATIVE BIOINFORMATICS. 2016 December; 13 (5): 57–69. doi:10.2390/biecoll-jib-2016-308.

Arslan, Nur; Guzel, Orkide; Kose, Engin; Yilmaz, Unsal; Kuyum, Pinar; Aksoy, Betul; Calik, Tansel. Is ketogenic diet treatment hepatotoxic for children with intractable epilepsy?. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY. 2016 December; 43: 32-38. doi:10.1016/j.seizure.2016.10.024.

Durmaz, Irem; Guven, Ebru Bilget; Ersahin, Tulin; Ozturk, Mehmet; Calis, Ihsan; Cetin-Atalay, Rengul. Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status. PHYTOMEDICINE. 2016 December; 23 (1): 42-51. doi:10.1016/j.phymed.2015.11.012.

Karakulah, Gokhan; Kurtoglu, Kuaybe Yucebilgili; Unver, Turgay. PeTMbase: A Database of Plant Endogenous Target Mimics (eTMs). PLOS ONE. 2016 December; 11 (12). doi:10.1371/journal.pone.0167698.

Marsano, Anna; da Cunha, Carolina M. Medeiros; Ghanaati, Shahram; Gueven, Sinan; Centola, Matteo; Tsaryk, Roman; Barbeck, Mike; Stuedle, Chiara; Barbero, Andrea; Helmrich, Uta; Schaeren, Stefan; Kirkpatrick, James C.; Banfi, Andrea; Martin, Ivan. Spontaneous In Vivo Chondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells by Blocking Vascular Endothelial Growth Factor Signaling. STEM CELLS TRANSLATIONAL MEDICINE. 2016 December; 5 (12): 1730-1738. doi:10.5966/sctm.2015-0321.

Erbayraktar, Zubeyde; Alural, Begum; Erbayraktar, Resat Serhat; Erkan, Erdogan Pekcan. Cell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness. CANCER CELL INTERNATIONAL. 2016 November; 16. doi:10.1186/s12935-016-0364-8.

* Adhikari, Deepak; Busayavalasa, Kiran; Zhang, Jingjing; Hu, Mengwen; Risal, Sanjiv; Bayazit, Mustafa Bilal; Singh, Meenakshi; Diril, M. Kasim; Kaldis, Philipp; Liu, Kui. Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan. CELL RESEARCH. 2016 November; 26 (11): 1212-1225. doi:10.1038/cr.2016.119.

Ferroudj, Sana; Yildiz, Gokhan; Bouras, Mourad; Iscan, Evin; Ekin, Umut; Ozturk, Mehmet. Role of Fanconi anemia/BRCA pathway genes in hepatocellular carcinoma chemoresistance. HEPATOLOGY RESEARCH. 2016 November; 46 (12): 1264-1274. doi:10.1111/hepr.12675.

Mustufa, Muhammad Ayaz; Ozen, Cigdem; Hashmi, Imran Ali; Aslam, Afshan; Baig, Jameel Ahmed; Yildiz, Gokhan; Muhammad, Shoaib; Solangi, Imam Bakhsh; Naqvi, Naim ul Hasan; Ozturk, Mehmet; Ali, Firdous Imran. Synthesis and bio-molecular study of (+)-N-Acetyl-a-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma. BMC CANCER. 2016 November; 16. doi:10.1186/s12885-016-2942-5.

* Jung-Woong Kim, Hyun-Jin Yang, Matthew John Brooks, Lina Zelinger, Gökhan Karakülah, Norimoto Gotoh, Alexis Boleda, Linn Gieser, Felipe Giuste, Dustin Thad Whitaker, Ashley Walton, Rafael Villasmil, Jennifer Joanna Barb, Peter Jonathan Munson, Koray Dogan Kaya, Vijender Chaitankar, Tiziana Cogliati, Anand Swaroop. NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors. Cell Reports. 2016 November; 17 (9): 2460-2473. doi:10.1016/j.celrep.2016.10.074.

Pavlopoulou, Athanasia; Oktay, Yavuz; Vougas, Konstantinos; Louka, Maria; Vorgias, Constantinos E.; Georgakilas, Alexandros G.. Determinants of resistance to chemotherapy and ionizing radiation in breast cancer stem cells. CANCER LETTERS. 2016 October; 380 (2): 485-493. doi:10.1016/j.canlet.2016.07.018.

Carr BI, Guerra V, Giannini EG, Farinati F, Ciccarese F, Rapaccini GL, Di Marco M, Benvegnù L, Zoli M, Borzio F, Caturelli E, Masotto A, Trevisani F. A Liver Index and its Relationship to Indices of HCC Aggressiveness. J Integr Oncol. 2016 October; 5 (4): 178. doi:10.4172/2329-6771.1000178.

* Chauhan, Sangeeta; Diril, M. Kasim; Lee, Joanna H. S.; Bisteau, Xavier; Manoharan, Vanessa; Adhikari, Deepak; Ratnacaram, Chandrahas Koumar; Janela, Baptiste; Noffke, Juliane; Ginhoux, Florent; Coppola, Vincenzo; Liu, Kui; Tessarollo, Lino; Kaldis, Philipp. Cdk2 catalytic activity is essential for meiotic cell division in vivo. BIOCHEMICAL JOURNAL. 2016 September; 473: 2783-2798. doi:10.1042/BCJ20160607.

Erkan, Deniz; Kayali, Hulya Ayar. Replacement of Soybean Meal with Animal Origin Protein Meals Improved Ramoplanin A2 Production by Actinoplanes sp ATCC 33076. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. 2016 September; 180 (2): 306-321. doi:10.1007/s12010-016-2100-1.

Karakulah, G.; Karakus, M.; Suner, A.; Demir, S.; Arserim, S. K.; Toz, S.; Ozbel, Y.. sandflyDST: a dynamic web-based decision support tool for the morphological identification of sandflies present in Anatolia and mainland Europe, and user study. MEDICAL AND VETERINARY ENTOMOLOGY. 2016 September; 30 (3): 321-329. doi:10.1111/mve.12182.

* Copf T. Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments. Neuroscience and biobehavioral reviews. 2016 September; 68: 946-978. doi:10.1016/j.neubiorev.2016.04.008.

Akdogan Y, Emrullahoglu M, Tatlidil D, Ucuncu M, Cakan-Akdogan G. EPR studies of intermolecular interactions and competitive binding of drugs in a drug-BSA binding model. Physical chemistry chemical physics : PCCP. 2016 August; 18 (32): 22531-9. doi:10.1039/c6cp04137j.

Mazzocca, Antonio; Ferraro, Giovanni; Misciagna, Giovanni; Carr, Brian I.. A systemic evolutionary approach to cancer: Hepatocarcinogenesis as a paradigm. MEDICAL HYPOTHESES. 2016 August; 93: 132-137. doi:10.1016/j.mehy.2016.05.027.

Wingender, Gerhard. From the Deep Sea to Everywhere: Environmental Antigens for iNKT Cells. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS. 2016 August; 64 (4): 291-298. doi:10.1007/s00005-015-0381-7.

Alagoz, Yagiz; Gurkok, Tugba; Zhang, Baohong; Unver, Turgay. Manipulating the Biosynthesis of Bioactive Compound Alkaloids for Next-Generation Metabolic Engineering in Opium Poppy Using CRISPR-Cas 9 Genome Editing Technology. SCIENTIFIC REPORTS. 2016 August; 6. doi:10.1038/srep30910.

Bakir, Yakup; Eldem, Vahap; Zararsiz, Gokmen; Unver, Turgay. Global Transcriptome Analysis Reveals Differences in Gene Expression Patterns Between Nonhyperhydric and Hyperhydric Peach Leaves. PLANT GENOME. 2016 July; 9 (2). doi:10.3835/plantgenome2015.09.0080.

Gao, Li-Min; Zhao, Sha; Liu, Wei-Ping; Zhang, Wen-Yan; Li, Gan-Di; Kucuk, Can; Hu, Xiao-Zhou; Chan, Wing C.; Tang, Yuan; Ding, Wen-Shuang; Yan, Jia-Qi; Yao, Wen-Qing; Wang, Jian Chao. Clinicopathologic Characterization of Aggressive Natural Killer Cell Leukemia Involving Different Tissue Sites. AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2016 June; 40 (6): 836-846. doi:10.1097/PAS.0000000000000634.

Kucuk, Can; Hu, Xiaozhou; Gong, Qiang; Jiang, Bei; Cornish, Adam; Gaulard, Philippe; McKeithan, Timothy; Chan, Wing C.. Diagnostic and Biological Significance of KIR Expression Profile Determined by RNA-Seq in Natural Killer/T-Cell Lymphoma. AMERICAN JOURNAL OF PATHOLOGY. 2016 June; 186 (6): 1435-1441. doi:10.1016/j.ajpath.2016.02.011.

Oktay, Yavuz; Ulgen, Ege; Can, Ozge; Akyerli, Cemaliye B.; Yuksel, Sirin; Erdemgil, Yigit; Durasi, I. Melis; Henegariu, Octavian Ioan; Nanni, E. Paolo; Selevsek, Nathalie; Grossmann, Jonas; Erson-Omay, E. Zeynep; Bai, Hanwen; Gupta, Manu; Lee, William; Turcan, Sevin; Ozpinar, Aysel; Huse, Jason T.; Sav, M. Aydin; Flanagan, Adrienne; Gunel, Murat; Sezerman, O. Ugur; Yakicier, M. Cengiz; Pamir, M. Necmettin; Ozduman, Koray. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. SCIENTIFIC REPORTS. 2016 June; 6. doi:10.1038/srep27569.

Safari, Roghaiyeh; Salimi, Reza; Tunca, Zeliha; Ozerdem, Aysegul; Ceylan, Deniz; Sakizli, Meral. Mutation/SNP analysis in EF-hand calcium binding domain of mitochondrial Ca2+ uptake 1 gene in bipolar disorder patients. JOURNAL OF INTEGRATIVE NEUROSCIENCE. 2016 June; 15 (2): 163-173. doi:10.1142/S0219635216500096.

Brian I Carr, Vito Guerra, Edoardo G. Giannini, Fabio Farinati, Francesca Ciccarese, Gian Ludovico Rapaccini, Maria Di Marco, Luisa Benvegnù, Marco Zoli, Franco Borzio, Eugenio Caturelli, Alberto Masotto and Franco Trevisani. An HCC Aggressiveness Index and Blood GTP, Blirubin and Platelet Levels. J. Integrative Oncology. 2016 June; 5 (2): 172. doi:10.4172/2329-6771.1000172.

Yilmaz Y, Atabey N, Erdal E & Brian I. Carr. Platelets, Microenvironment and Hepatocellular Carcinoma. Biochemistry & Analytical Biochemistry. 2016 June; 5: 281. doi:10.4172/2161-1009.1000281.

Salimi, Reza; Yener, Nilgun; Safari, Roghaiyeh. Use and Evaluation of Newly Synthesized Fluorescence Probes to Detect Generated OHaEuro cent Radicals in Fibroblast Cells. JOURNAL OF FLUORESCENCE. 2016 May; 26 (3): 919-924. doi:10.1007/s10895-016-1780-9.

Guzel, Orkide; Yilmaz, Unsal; Uysal, Utku; Arslan, Nur. The effect of olive oil-based ketogenic diet on serum lipid levels in epileptic children. NEUROLOGICAL SCIENCES. 2016 March; 37 (3): 465-470. doi:10.1007/s10072-015-2436-2.

Carr, Brian I.; Guerra, Vito. Low Alpha-Fetoprotein Levels Are Associated with Improved Survival in Hepatocellular Carcinoma Patients with Portal Vein Thrombosis. DIGESTIVE DISEASES AND SCIENCES. 2016 March; 61 (3): 937-947. doi:10.1007/s10620-015-3922-3.

Namkoong B, Güven S, Ramesan S, Liaudanskaya V, Abzhanov A, Demirci U. Recapitulating cranial osteogenesis with neural crest cells in 3-D microenvironments. Acta biomaterialia. 2016 February; 31: 301-311. doi:10.1016/j.actbio.2015.12.004.

Firtina Karagonlar Z, Koç D, Şahin E, Avci ST, Yilmaz M, Atabey N, Erdal E. Effect of adipocyte-secreted factors on EpCAM+/CD133+ hepatic stem cell population. Biochemical and biophysical research communications. 2016 January; 474 (3): 482-490. doi:10.1016/j.bbrc.2016.04.137.

Firtina Karagonlar Z, Koc D, Iscan E, Erdal E, Atabey N. Elevated hepatocyte growth factor expression as an autocrine c-Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells. Cancer science. 2016 January; 107 (4): 407-16. doi:10.1111/cas.12891.

* Bouyer C, Chen P, Güven S, Demirtaş TT, Nieland TJ, Padilla F, Demirci U. A Bio-Acoustic Levitational (BAL) Assembly Method for Engineering of Multilayered, 3D Brain-Like Constructs, Using Human Embryonic Stem Cell Derived Neuro-Progenitors. Advanced materials (Deerfield Beach, Fla.). 2016 January; 28 (1): 161-7. doi:10.1002/adma.201503916.

Carr, Brian I.; Guerra, Vito. A Hepatocellular Carcinoma Aggressiveness Index and Its Relationship to Liver Enzyme Levels. ONCOLOGY. 2016 ; 90 (4): 215-220. doi:10.1159/000444394.

Erkan, Erdogan Pekcan; Vurgun, Ufuk; Erbayraktar, Resat Serhat; Erbayraktar, Zubeyde. Glioblastoma stem cells: a therapeutic challenge. TURKISH JOURNAL OF BIOLOGY. 2016 ; 40 (5): 990-997. doi:10.3906/biy-1508-79.

Carr, Brian I.; Guerra, Vito. Hepatocellular Carcinoma Extrahepatic Metastasis in Relation to Tumor Size and Alkaline Phosphatase Levels. ONCOLOGY. 2016 ; 90 (3): 136-142. doi:10.1159/000443480.

Jeannot, Victor; Busser, Benoit; Vanwonterghem, Laetitia; Michallet, Sophie; Ferroudj, Sana; Cokol, Murat; Coll, Jean-Luc; Ozturk, Mehmet; Hurbin, Amandine. Synergistic activity of vorinostat combined with gefitinib but not with sorafenib in mutant KRAS human non-small cell lung cancers and hepatocarcinoma. ONCOTARGETS AND THERAPY. 2016 ; 9: 6843-6855. doi:10.2147/OTT.S117743.